PEG 400 as a reusable solvent for 1, 4-dipolar cycloadditions via a three-component reaction

Subba Reddy, B. V. ; Somashekar, D. ; Mallikarjun Reddy, A. ; Yadav, J. S. ; Sridhar, Balasubramanian (2010) PEG 400 as a reusable solvent for 1, 4-dipolar cycloadditions via a three-component reaction Synthesis, 2010 (12). pp. 2069-2074. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-0029-1218762

Abstract

Isocyanides, dialkyl acetylenedicarboxylates, and α,β-unsaturated aldehydes undergo smooth condensation in poly(ethylene glycol) (PEG 400) to afford the corresponding styrylfuran derivatives in good yields. This method provides a convenient route for a wide range of styrylfurans in a one-pot operation via a three-component reaction. The solvent can be recycled and reused for further reactions.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Poly(Ethylene Glycol); Three-component Reaction; Zwitterions; Styrylfurans
ID Code:63134
Deposited On:28 Sep 2011 03:44
Last Modified:28 Sep 2011 03:44

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