Phosphomolybdic acid supported on silica gel as mild, efficient and cost-effective catalyst for chemoselective protection of amines with di-tert-butyl dicarbonate

Yadav, J. S. ; Rao, Y. G. ; Ramesh Reddy, A. ; Narasaiah, A. V. ; Subba Reddy, B. V. (2008) Phosphomolybdic acid supported on silica gel as mild, efficient and cost-effective catalyst for chemoselective protection of amines with di-tert-butyl dicarbonate Letters in Organic Chemistry, 5 (2). pp. 116-119. ISSN 1570-1786

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Official URL: http://www.ingentaconnect.com/content/ben/loc/2008...

Related URL: http://dx.doi.org/10.2174/157017808783743957

Abstract

A variety of amines were protected as their N-Boc derivatives using phosphomolybdic acid supported on silica gel as a heterogeneous catalyst. The catalyst is more effective and highly selective for the protection of amines under mild conditions and it can be recovered and reused in subsequent reactions without apparent loss of activity.

Item Type:Article
Source:Copyright of this article belongs to Bentham Science Publishers.
Keywords:Amines; Boc-anhydride; PMA-SiO2; Protection; Solid Acids
ID Code:63065
Deposited On:28 Sep 2011 03:39
Last Modified:28 Sep 2011 03:39

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