Yadav, J. S. ; Subba Reddy, B. V. ; Narasimhulu, G. ; Satheesh, G. (2009) First example of C-3 alkylation of indoles with activated azetidines catalyzed by indium(III) bromide Synlett, 2009 (5). pp. 727-730. ISSN 0936-5214
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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...
Related URL: http://dx.doi.org/10.1055/s-0028-1087957
Abstract
Indoles undergo smooth alkylation with N-tosylazetidines in the presence of indium(III) bromide in dichloroethane under mild conditions to produce the corresponding C-3 substituted indole derivatives in good to high yields and with high selectivity. This is the first report on the alkylation of indoles with activated azetidines.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers. |
| Keywords: | Indoles; Indium(III) Bromide; Activated Azetidine; C-3 Alkylation |
| ID Code: | 62961 |
| Deposited On: | 24 Sep 2011 04:59 |
| Last Modified: | 24 Sep 2011 04:59 |
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