Yadav, Jhillu S. ; Subba Reddy, Basi V. ; Yadav, Nagendra Nath ; Gupta, Manoj K. (2009) Three-component coupling of isoquinoline, activated alkyne and nitromethane: a facile synthesis of nitromethyl derivatives of 1,2-dihydroisoquinolines Synthesis, 2009 (7). pp. 1131-1136. ISSN 0039-7881
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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...
Related URL: http://dx.doi.org/10.1055/s-0028-1088004
Abstract
A three-component coupling (3CC) of isoquinoline, activated alkynes and nitromethane has been achieved for the first time to produce nitromethyl derivatives of dihydroisoquinoline in excellent yields with high selectivity. The reaction proceeds smoothly at 25 °C without catalyst.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers. |
| Keywords: | Aza-henry Reaction; Isoquinoline/Quinoline; Activated Alkynes; Nitromethane |
| ID Code: | 62861 |
| Deposited On: | 24 Sep 2011 04:59 |
| Last Modified: | 24 Sep 2011 04:59 |
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