An efficient synthesis of 2H-1, 4-benzoxazin-3 (4H)-ones via Smiles rearrangement

Kang, Jongphil ; Kam, Kyeong-Hee ; Ghate, Manjunath ; Hua, Zuo ; Kim, Tae-Hyun ; Raji Reddy, Ch. ; Chandrasekhar, S. ; Shina, Dong-Soo (2008) An efficient synthesis of 2H-1, 4-benzoxazin-3 (4H)-ones via Smiles rearrangement ARKIVOC: Online Journal of Organic Chemistry, 2008 . pp. 67-76. ISSN 1424-6376

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Official URL: http://www.arkat-usa.org/get-file/26130/

Abstract

A novel and effective synthesis of substituted 1,4-benzoxazinones via Smiles rearrangement is described. Treatment of N-substituted 2-chloroacetamide, substituted 2-chlorophenols and cesium carbonate in refluxing DMF afforded the corresponding substituted 1,4-benzoxazinones in excellent yield.

Item Type:Article
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Keywords:1,4-oxazinone; Smiles Rearrangement; 1,4-benzoxazin-3-one; Cesium Carbonate
ID Code:62364
Deposited On:22 Sep 2011 03:33
Last Modified:22 Sep 2011 03:33

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