Tris(pentafluorophenyl)borane-catalyzed three-component reaction for the synthesis of 1,8-dioxodecahydroacridines under solvent-free conditions

Chandrasekhar, Srivari ; Srinivasa Rao, Yaragorla ; Sreelakshmi, Lella ; Mahipal, Bodugam ; Raji Reddy, Chada (2008) Tris(pentafluorophenyl)borane-catalyzed three-component reaction for the synthesis of 1,8-dioxodecahydroacridines under solvent-free conditions Synthesis, 2008 (11). pp. 1737-1740. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2008-1067039

Abstract

A mild and efficient method for the synthesis of 1,8-dioxodecahydroacridines has been developed. The synthesis proceeds via a three-component reaction of a 1,3-dione, an aldehyde and an amine, under solvent-free conditions, catalyzed by tris(pentafluorophenyl)borane [B(C6F5)3]. The mildness of the catalyst was demonstrated by studying the reaction of 1,3-cyclohexanedione with various aldehydes and amines which gave the 1,8-dioxodecahydroacridines in high yields.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Hantzsch Reaction; Acridinediones; Tris(pentafluorophenyl)borane; Three-component Reaction; Lewis Acid
ID Code:62360
Deposited On:22 Sep 2011 03:33
Last Modified:22 Sep 2011 03:33

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