Yadav, J. S. ; Thirupathaiah, B. ; Srihari, P. (2010) A concise stereoselective total synthesis of (+)-artemisinin Tetrahedron, 66 (11). pp. 2005-2009. ISSN 0040-4020
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tet.2010.01.051
Abstract
A protective group free, concise, and stereoselective total synthesis of (+)-artemisinin, starting from readily available (R)-(+)-citronellal, is described. Asymmetric 1, 4-addition, Aldol condensation, Ene reaction, regioselective hydroboration are the key steps involved in the total synthesis of the target molecule.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
ID Code: | 59555 |
Deposited On: | 07 Sep 2011 05:58 |
Last Modified: | 07 Sep 2011 05:58 |
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