First example of FeCl3-catalyzed alkylation of indoles with pinenes

Yadav, J. S. ; Subba Reddy, B. V. ; Narasimhulu, G. ; Sivasankar Reddy, N. ; Narayana Reddy, P. ; Purnima, K. V. ; Naresh, P. ; Jagadeesh, B. (2010) First example of FeCl3-catalyzed alkylation of indoles with pinenes Tetrahedron Letters, 51 (2). pp. 244-247. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.10.128

Abstract

Indoles undergo smooth alkylation with α- and β-pinenes in the presence of 20 mol % of anhydrous FeCl3 under mild reaction conditions to produce a wide range of the corresponding 3-alkylated indoles in excellent yields with high trans-selectivity. This is the first example of alkylation of indoles with mono-terpenes.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Terpenes; Iron(III) Reagents; Alkylation; Indoles
ID Code:58957
Deposited On:02 Sep 2011 03:39
Last Modified:02 Sep 2011 03:39

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