Phosphomolybdic acid-supported silica gel as efficient and cost-effective solid acid for the benzylation of indoles with benzylic alcohols

Yadav, J. S. ; Subba Reddy, B. V. ; Srinivas Reddy, A. (2008) Phosphomolybdic acid-supported silica gel as efficient and cost-effective solid acid for the benzylation of indoles with benzylic alcohols Journal of Molecular Catalysis A: Chemical, 280 (1-2). pp. 219-223. ISSN 1381-1169

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.molcata.2007.10.004

Abstract

Indoles undergo smooth alkylation with benzylic alcohols on the surface of 10 mol% of phosphomolybdic acid supported on silica gel under mild conditions to produce C-3 benzylated-indoles in high yields and with high selectivity. This method offers significant advantages such as high conversions, short reaction times, mild reaction conditions, cleaner reaction profiles, high selectivity and low cost of the heterogeneous catalyst.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Heteropolyacid; Solid-supported Catalysts; Benzylic Alcohols; Indoles
ID Code:58918
Deposited On:02 Sep 2011 03:30
Last Modified:02 Sep 2011 03:30

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