Diels-Alder approach towards the stereocontrolled construction of a taxol® C ring fragment

Yadav, J. S. ; Sasmal, Pradip K. (1999) Diels-Alder approach towards the stereocontrolled construction of a taxol® C ring fragment Tetrahedron, 55 (16). pp. 5185-5194. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4020(99)00165-9

Abstract

An elegant stereocontrolled synthesis of a highly functionalized C ring fragment of taxol® is described. The route utilises a new Diels-Alder reaction followed by regioselective opening of anhydride, reductive dechlorination, Baeyer-Villiger oxidation of norbornenone system and stereodirected hydroboration using thexylborane as the key steps.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:58860
Deposited On:02 Sep 2011 03:10
Last Modified:10 Oct 2011 04:50

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