Stereoselective total synthesis of 5(S), 6(R), 15(S)-trihydroxy-7(E), 9(E), 11(Z),13(E)-eicosatetraenoic acid (lipoxin A)

Yadav, J. S. ; Barma, D. K. ; Dutta, Dinah (1998) Stereoselective total synthesis of 5(S), 6(R), 15(S)-trihydroxy-7(E), 9(E), 11(Z),13(E)-eicosatetraenoic acid (lipoxin A) Tetrahedron Letters, 39 (1-2). pp. 143-146. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(97)10471-3

Abstract

A stereoselective synthesis of the title compound from D-xylose using zinc mediated deoxygenation of 4-hydroxy-2-butenoic acid moiety and base induced double elimination of 4,5-epoxy allyl chloride as key steps is described.

Item Type:Article
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ID Code:58754
Deposited On:02 Sep 2011 03:09
Last Modified:02 Sep 2011 03:09

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