Khan, Z. U. ; Sanyal, S. C. ; Mokaddas, Eiman ; Vislocky, I. ; Anim, J. T. ; Salama, A. L. ; Shuhaiber, H. (1997) Endocarditis due to Aspergillus flavus Mycoses, 40 (5-6). pp. 213-217. ISSN 0933-7407
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-...
Related URL: http://dx.doi.org/10.1111/j.1439-0507.1997.tb00217.x
Abstract
Fungal endocarditis has emerged as an important complication of patients undergoing cardiovascular surgery. Our patient had no past history of cardiac surgery, intravenous drug abuse or immunosuppressive therapy. He had received broad-spectrum antibiotics for varying periods, which might have predisposed him to this infection. The diagnosis was based on the demonstration of hyaline, septate branched fungal elements in the infected valvular tissue and isolation of Aspergillus flavus in culture. The delay in establishing the ante-mortem diagnosis because of repeatedly negative blood cultures, presence of disseminated intravascular coagulopathy and rapidly deteriorating kidney function were the major factors contributing to his poor prognosis and death, despite surgical removal of infected valves and antifungal therapy. This is the first report of endocarditis due to A. flavus from the Middle East.
Item Type: | Article |
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Source: | Copyright of this article belongs to John Wiley and Sons. |
Keywords: | Aspergillus flavous; Aspergillosis; Endocarditis; Predisposing Factors; Aspergillus flavus; Aspergillose; Endokarditis; Prädispositionsfaktoren |
ID Code: | 49244 |
Deposited On: | 20 Jul 2011 06:36 |
Last Modified: | 20 Jul 2011 06:36 |
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