The first enantiospecific synthesis of (+)-10,11-epoxythapsan-10-ol: revision of the absolute stereochemistry of thapsanes

Srikrishna, A. ; Anebouselvy, K. (2002) The first enantiospecific synthesis of (+)-10,11-epoxythapsan-10-ol: revision of the absolute stereochemistry of thapsanes Tetrahedron Letters, 43 (30). pp. 5261-5264. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)01051-1

Abstract

The first enantiospecific synthesis of (+)-cis,anti,cis-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.02,6]dodecan-3-ol (+)-1g, an enantiomer of natural thapsane isolated from Thapsia villosa var minor, is accomplished starting from (R)-carvone, which revises the absolute stereochemistry of natural thapsanes.

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Deposited On:15 Jul 2011 11:41
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