Srividhya, V. ; Savithri, H. S. (1996) Interactions of 3' terminal and 5' terminal regions of physalis mottle virus genomic RNA with its replication complex Journal of Biosciences, 21 (6). pp. 743-753. ISSN 0250-5991
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Official URL: http://www.ias.ac.in/jarch/jbiosci/21/743-753.pdf
Related URL: http://dx.doi.org/10.1007/BF02704715
Abstract
Physalis mottle virus (PhMV) belongs to the tymogroup of positive-strand RNA viruses with a genome size of 6 kb. Crude membrane preparations from PhMV-infectedNicotiana glutinosa plants catalyzed the synthesis of PhMV genomic RNA from endogenously bound template. Addition of exogenous gnomic RNA enhanced the synthesis which was specifically inhibited by the addition of sense and antisense transcripts corresponding to 3' terminal 242 nucleotides as well as the 5' terminal 458 nucleotides of PhMV genomic RNA while yeast tRNA or ribosomal RNA failed to inhibit the synthesis. This specific inhibition suggested that the 5' and 3' non-coding regions of PhMV RNA might play an important role in viral replication.
Item Type: | Article |
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Source: | Copyright of this article belongs to Indian Academy of Sciences. |
Keywords: | Physalis Mottle Virus; Replication; Inhibition; SSRNA Plant Virus |
ID Code: | 45954 |
Deposited On: | 29 Jun 2011 09:52 |
Last Modified: | 18 May 2016 02:02 |
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