Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells

Dhir, Haimanti ; Sharma, Archana ; Talukder, Geeta (1992) Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells Biological Trace Element Research, 34 (3). pp. 279-286. ISSN 0163-4984

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Official URL: http://www.springerlink.com/content/c8t6771r38346h...

Related URL: http://dx.doi.org/10.1007/BF02783683

Abstract

Essential trace elements such as iron (Fe) are known to interact with nonessential metals like lead (Pb), influencing its metabolism. Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration.

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Deposited On:05 May 2011 14:04
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