Guanacastepene-A total synthesis: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks

Mehta, Goverdhan ; Umarye, Jayant D. ; Srinivas, Kalidindi (2003) Guanacastepene-A total synthesis: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks Tetrahedron Letters, 44 (22). pp. 4233-4237. ISSN 0040-4039

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Official URL: http://dx.doi.org/10.1016/S0040-4039(03)00883-9

Related URL: http://dx.doi.org/10.1016/S0040-4039(03)00883-9

Abstract

Studies aimed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug resistant pathogens has led to the generation of some novel tricyclic skeleta replete with extensive functionalization and representing interesting variations of the guanacastepane framework.

Item Type:	Article
Source:	Copyright of this article belongs to Elsevier Science.
ID Code:	29092
Deposited On:	18 Dec 2010 05:37
Last Modified:	17 May 2016 12:04

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