A view-based approach for the reconstruction of optical properties of turbid media

Abstract

A view-based approach for the computation of updates of optical parameters of a turbid medium is discussed. The approach differs from conventionally employed reconstruction techniques in terms of implementation of the computed updates. Simulation studies in frequency domain for tissue phantoms approximated by slab geometry have been presented. Results of the study show that the proposed inversion scheme, wherein the projection data corresponding to each view has been handled individually, works well in predicting the presence of an inhomogeneity. A comparison with the reconstruction results of conventionally employed inversion schemes involving simultaneous handling of projection data from all the view angles shows that the accuracy of the proposed scheme in predicting the presence of single inhomogeneity is higher and the reconstruction is also relatively free of artifacts. On the other hand, in the presence of multiple inhomogeneities, though the simultaneous handling of all the views gives better reconstruction, the updates obtained by the proposed scheme can be employed as close a priori information about the approximate positions of the inhomogeneities, thereby reducing the overall dimension of the Jacobian matrix to be inverted and hence making the convergence faster.