Krishnamoorthy, G. ; Ira, (2001) Fluorescence lifetime distribution in characterizing membrane microheterogeneity Journal of Fluorescence, 11 (4). pp. 247-253. ISSN 1053-0509
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Official URL: http://www.springerlink.com/content/q9q75247448143...
Related URL: http://dx.doi.org/10.1023/A:1013943721692
Abstract
Realistic description of biomembrane heterogeneity is essential for understanding the complexity of their function. Application of the distribution of the fluorescence lifetime of membrane probes, especially by the maximum entropy method, in studying membrane heterogeneity is described. Representative studies on various membranes and the information brought out in these studies are reviewed. An example is provided wherein the water-wire hypothesis of transmembrane proton transport gets experimental support from Nile Red fluorescence lifetime distribution analysis. Future directions in the use of this methodology in cell physiology are indicated.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer-Verlag. |
| Keywords: | Fluorescence Lifetime Distribution; Maximum Entropy Method; Membrane Microheterogeneity; Time-resolved Fluorescence Microscopy |
| ID Code: | 18009 |
| Deposited On: | 17 Nov 2010 13:21 |
| Last Modified: | 04 Jun 2011 04:17 |
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