Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial

Bhandari, Nita ; Rongsen-Chandola, Temsunaro ; Bavdekar, Ashish ; John, Jacob ; Antony, Kalpana ; Taneja, Sunita ; Goyal, Nidhi ; Kawade, Anand ; Kang, Gagandeep ; Rathore, Sudeep Singh ; Juvekar, Sanjay ; Muliyil, Jayaprakash ; Arya, Alok ; Shaikh, Hanif ; Abraham, Vinod ; Vrati, Sudhanshu ; Proschan, Michael ; Kohberger, Robert ; Thiry, Georges ; Glass, Roger ; Greenberg, Harry B ; Curlin, George ; Mohan, Krishna ; Harshavardhan, G V J A ; Prasad, Sai ; Rao, T S ; Boslego, John ; Bhan, Maharaj Kishan (2014) Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial The Lancet, 383 (9935). pp. 2136-2143. ISSN 0140-6736

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Official URL: http://doi.org/10.1016/S0140-6736(13)62630-6

Related URL: http://dx.doi.org/10.1016/S0140-6736(13)62630-6

Abstract

Rotavirus is the most common cause of severe dehydrating gastroenteritis in developing countries. Safe, effective, and affordable rotavirus vaccines are needed in these countries. We aimed to assess the efficacy and tolerability of a monovalent human-bovine rotavirus vaccine for severe rotavirus gastroenteritis in low-resource urban and rural settings in India.

Item Type:Article
Source:Copyright of this article belongs to The Lancet.
ID Code:135832
Deposited On:22 Aug 2023 11:43
Last Modified:22 Aug 2023 11:43

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