Pan, Uday Narayan ; Sanpui, Pallab ; Paul, Anumita ; Chattopadhyay, Arun (2018) Surface-Complexed Zinc Ferrite Magnetofluorescent Nanoparticles for Killing Cancer Cells and Single-Particle-Level Cellular Imaging ACS Applied Nano Materials, 1 (6). pp. 2496-2502. ISSN 2574-0970
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Official URL: http://doi.org/10.1021/acsanm.8b00545
Related URL: http://dx.doi.org/10.1021/acsanm.8b00545
Abstract
The fabrication of novel magnetofluorescent nanoparticles (NPs) by complexation of zinc ions present on the surface of a zinc ferrite nanoparticle (ZnFe2O4 NP) with 8-hydroxy-2-quinolinecarboxaldehyde (HQCald) is reported. The as-prepared HQCald-complexed ZnFe2O4 NPs showed good quantum yield (3.62%), high photostability, considerable excited-state lifetime (5.31 ns), and high saturation magnetization (12.7 emu/g). These magnetofluorescent NPs demonstrated bioimaging capability at both the ensemble- and single-particle levels and in vitro magnetic targeting. Moreover, the pronounced antiproliferative efficacy of these NPs against cancer cells, with appropriate targeting strategies, can lead to potential cancer theranostics.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society |
| Keywords: | Single-particle-level cellular imaging; multifunctional theranostic nanoparticles; surface complexation; magnetic targeting; antiproliferative efficacy |
| ID Code: | 135451 |
| Deposited On: | 24 Jan 2023 05:41 |
| Last Modified: | 24 Jan 2023 05:41 |
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