An Expedient Total Synthesis of cis-(+)-Sertraline from d-Phenylglycine

Chandrasekhar, S. ; Venkat Reddy, M. (2000) An Expedient Total Synthesis of cis-(+)-Sertraline from d-Phenylglycine Tetrahedron, 56 (8). pp. 1111-1114. ISSN 00404020

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Official URL: http://doi.org/10.1016/S0040-4020(99)01067-4

Related URL: http://dx.doi.org/10.1016/S0040-4020(99)01067-4

Abstract

An efficient and practical total synthesis of cis-(+)-Sertraline is developed involving intramolecular Friedel–Crafts cyclization of an appropriately tailored d-phenylglycine.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science Ltd
Keywords:Friedel–Crafts cyclization;serotonin;antidepressants
ID Code:131525
Deposited On:07 Dec 2022 04:26
Last Modified:07 Dec 2022 04:26

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