Total synthesis of pyrrolidine alkaloid, Radicamine-B via Stille coupling

Mallesham, P. ; Vijaykumar, B.V.D. ; Shin, Dong-Soo ; Chandrasekhar, S. (2011) Total synthesis of pyrrolidine alkaloid, Radicamine-B via Stille coupling Tetrahedron Letters, 52 (46). pp. 6145-6147. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2011.09.034

Related URL: http://dx.doi.org/10.1016/j.tetlet.2011.09.034

Abstract

Total synthesis of (−) Radicamine-B is achieved in eight steps from (R)-(+)-Garner aldehyde in a stereoflexible manner involving Stille coupling and one-pot domino epoxidation-pyrrolidine formation as key steps.

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ID Code:131366
Deposited On:06 Dec 2022 11:25
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