Asymmetric Syntheses of All Stereoisomers of 3-Hydroxyproline; A Constituent of Several Bioactive Compounds

Chandrasekhar, Srivari ; Kumar, Togapur (2012) Asymmetric Syntheses of All Stereoisomers of 3-Hydroxyproline; A Constituent of Several Bioactive Compounds Synthesis, 44 (18). pp. 2889-2894. ISSN 0039-7881

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Official URL: http://doi.org/10.1055/s-0032-1316734

Related URL: http://dx.doi.org/10.1055/s-0032-1316734

Abstract

Synthesis of an unusual β-hydroxy-α-amino acid, 3-hydroxyproline, and its derivatives have been achieved enantioselectively by employing Sharpless asymmetric epoxidation and reductive cyclization as the key steps.

Item Type:Article
Source:Copyright of this article belongs to Georg Thieme Verlag KG
ID Code:131353
Deposited On:06 Dec 2022 11:01
Last Modified:06 Dec 2022 11:01

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