Deshmukh, Pratiksha P. ; Navalkar, Ambuja ; Maji, Samir K. ; Manjare, Sudesh T. (2019) Phenylselenyl containing turn-on dibodipy probe for selective detection of superoxide in mammalian breast cancer cell line Sensors and Actuators B: Chemical, 281 . pp. 8-13. ISSN 09254005
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Official URL: http://doi.org/10.1016/j.snb.2018.10.072
Related URL: http://dx.doi.org/10.1016/j.snb.2018.10.072
Abstract
A monoselenium containing diBODIPY-based probe was synthesized. The probe was found to be selective and sensitive for the detection of superoxide (KO2) over other reactive oxygen species through fluorescence turn-on event with 11-fold increase in fluorescence intensity. The detection limit was found to be 4.42 μM. The utility of the probe for detection of intracellular superoxide was demonstrated in a mammalian breast cancer cell line (MCF-7) through fluorescence microscopy.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier B.V |
| ID Code: | 126422 |
| Deposited On: | 31 Oct 2022 04:11 |
| Last Modified: | 31 Oct 2022 04:11 |
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