Dadwal, Mamta ; Mohan, Renu ; Panda, Dulal ; Mobin, Shaikh M. ; Namboothiri, Irishi N. N. (2006) The Morita–Baylis–Hillman adducts of β-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies Chemical Communications (3). pp. 338-340. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/b512267h
Related URL: http://dx.doi.org/10.1039/b512267h
Abstract
The Morita-Baylis-Hillman (MBH) adducts of β-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit HeLa cell proliferation by binding to tubulin.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to The Royal Society of Chemistry. |
| ID Code: | 121595 |
| Deposited On: | 19 Jul 2021 11:21 |
| Last Modified: | 19 Jul 2021 11:21 |
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