Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles

Ali, Md Ashif ; Punniyamurthy, Tharmalingam (2011) Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles Synlett, 2011 (05). pp. 623-626. ISSN 0936-5214

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Related URL: http://dx.doi.org/10.1055/s-0030-1259548

Abstract

The synthesis of polysubstituted indoles is described by the domino reaction of 2-haloanilines and 1,3-dicarbonyl compounds, 1,3-diketones, β-keto esters and β-keto amides, using copper catalysis under ligand-free conditions. The protocol provides a simple, general and atom economical process for the synthesis of substituted indoles at moderate temperature.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Cu2O; Indoles; Cesium Carbonate; 1,3-Dicarbonyl Compounds; 2-Haloanilines
ID Code:106442
Deposited On:22 Jun 2017 10:21
Last Modified:22 Jun 2017 10:21

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