Synthetic studies toward macrocidins: An RCM approach for the construction of the central cyclic core

Ramana, C. V. ; Mondal, Mohabul A. ; Puranik, Vedavati G. ; Gurjar, Mukund K. (2006) Synthetic studies toward macrocidins: An RCM approach for the construction of the central cyclic core Tetrahedron Letters, 47 (24). pp. 4061-4064. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.03.192

Abstract

The central macrocyclic core of the macrocidins was constructed using RCM as the key reaction. A preliminary investigation dealing with the key reactions, that is, the Dieckmann cyclization and the RCM, revealed that RCM of the β-ketoamide is better than RCM of the corresponding acyltetramic acid.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Macrocidins; Acyltetramic Acid; Lacey–Dieckmann Cyclization; Ring Closing Metathesis
ID Code:106158
Deposited On:01 Feb 2018 16:56
Last Modified:01 Feb 2018 16:56

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