Effects of the eye phase in DNA unzipping

Giri, Debaprasad ; Kumar, Sanjay (2006) Effects of the eye phase in DNA unzipping Physical Review E, 73 (5). Article ID 050903(R). ISSN 1539-3755

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Official URL: http://journals.aps.org/pre/abstract/10.1103/PhysR...

Related URL: http://dx.doi.org/10.1103/PhysRevE.73.050903

Abstract

The onset of the “eye phase” (a phase consisting of configurations of eye-type conformations or bubbles in the double-stranded DNA) and its role during the DNA unzipping is studied when a force is applied to the interior of the chain. The directionality of the hydrogen bond introduced here shows oscillations in force-extension curve similar to a “sawtooth” kind of oscillations seen in the protein unfolding experiments. The effects of intermediates (hairpins) and stacking energies on the melting profile have also been discussed.

Item Type:Article
Source:Copyright of this article belongs to American Physical Society.
ID Code:102710
Deposited On:02 Feb 2018 04:24
Last Modified:02 Feb 2018 04:24

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