@article{iaseprints73352, note = {Copyright of this article belongs to American Association for the Advancement of Science.}, number = {5959}, publisher = {American Association for the Advancement of Science}, title = {Mapping human genetic diversity in Asia}, journal = {Science}, author = {Mahmood Ameen Abdulla and Ikhlak Ahmed and Anunchai Assawamakin and Jong Bhak and Samir K. Brahmachari and Gayvelline C. Calacal and Amit Chaurasia and Chien-Hsiun Chen and Jieming Chen and Yuan-Tsong Chen and P. P.; . . . (The HUGO Pan-Asian SNP Consortium) . . . ; Majumder}, year = {2009}, pages = {1541--1545}, volume = {326}, month = {December}, url = {http://repository.ias.ac.in/73352/}, abstract = {Asia harbors substantial cultural and linguistic diversity, but the geographic structure of genetic variation across the continent remains enigmatic. Here we report a large-scale survey of autosomal variation from a broad geographic sample of Asian human populations. Our results show that genetic ancestry is strongly correlated with linguistic affiliations as well as geography. Most populations show relatedness within ethnic/linguistic groups, despite prevalent gene flow among populations. More than 90\% of East Asian (EA) haplotypes could be found in either Southeast Asian (SEA) or Central-South Asian (CSA) populations and show clinal structure with haplotype diversity decreasing from south to north. Furthermore, 50\% of EA haplotypes were found in SEA only and 5\% were found in CSA only, indicating that SEA was a major geographic source of EA populations.} }