Daniel, Clive Sunil ; Agarwal, Sarita ; Agarwal, Shyam S. (1986) Human red blood cell membrane damage by endosulfan Toxicology Letters, 32 (1-2). pp. 113-118. ISSN 0378-4274
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/037842...
Related URL: http://dx.doi.org/10.1016/0378-4274(86)90056-1
Abstract
Endosulfan is a chlorinated hydrocarbon insecticide. Its in vitro toxicity on human red blood cell membrane was studied by staining with a fluorochrome dye, merocyanine-540 (MC-540) and Scanning Electron muscopy (SEM). At a concentration of 0.001μg/ml(1 ppb) endosulfan was found to damage human red cell membranes as demonstrated by fluorescence of 30-50% of red cells on staining with MC-540. This was supported by the finding of crenation and threading of red blood cells under SEM. At concentration of 1μg/ml (1 ppm) the cells were markedly damaged.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Endosulfan Toxicity; Scanning Electron Muscopy; Merocyanine-540 |
| ID Code: | 81 |
| Deposited On: | 16 Sep 2010 10:56 |
| Last Modified: | 12 May 2011 04:08 |
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